Healthcare Professionals

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“ Pain at the time of vaccine injection is a common concern and contributes to vaccine hesitancy across the lifespan.”

Taddio et al, 2015⁴

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“ Young patients always report the pain of cannulation as one of the most painful aspects of being in a hospital ”

– Nurse Practitioner, Brisbane’s Lady Cilento Children’s Hospital⁶

Lidocaine (lignocaine) 2.5% w/w prilocaine 2.5% w/w combination cream can anaesthesia the full skin thickness – over 4 mm deep.⁷ ⁸

Two effective anaesthetics in liquid form provide enhanced skin penetration.⁹ Other anaesthetic droplets form a reservoir in the skin that continues to release after Numit is removed.¹⁰

Lidocaine (lignocaine) 2.5% w/w prilocaine 2.5% w/w combination cream can provide anaesthesia for at least 2 hours.¹¹ ⁷

Anaesthesia increases for UP TO 60 MINS after the occlusive wrapping is removed.⁷

References:

1. Britt H, Miller GC, Valenti L, Henderson J, Bayram C, Gordon J. The changing face of Australian general practice across the decades. Aust Fam Physician 2016; 45(9):628–3.

2. Britt H, Miller GC, Henderson J, Bayram C, Harrison C, Valenti L et al. General practice activity in Australia 2014–15. General practice series no. 38. Sydney: Sydney University Press, 2015.

3. Britt H, Miller GC, Charles J, Pan Y, Valenti L, Henderson J. General practice activity in Australia 2005–06. General practice series no. 19. AIHW cat. no. GEP 19. Canberra: Australian Institute of Health and Welfare. 2007.

4. Taddio A, McMurtry CM, Shah V, Riddell RP, Chambers CT, Noel M et al. Reducing pain during vaccine injections: clinical practice guideline. CMAJ 2015; 187(13):975–82.

5. Keogh S, Flynn J, Marsh N, Higgins N, Davies K, Rickard CM. Nursing and midwifery practice for maintenance of vascular access device patency. A cross-sectional survey. Int J Nurs Stud 2015; 52(11):1678–85.

6. ABC. Australia failing to meet best practice guidelines for IV treatment [internet]. 2016 [cited 2018 May 24]. Available from: https://www.abc.net.au/radionational/programs/breakfast/australia-fails-to-meet-best-practice-guidelines-iv-treatment/7379770

7. Bjerring P, Arendt-Nielsen L. Depth and duration of skin analgesia to needle insertion after topical application of Emla cream. Br J Anaesth 1990; 64(2):173–7.

8. NIH. National Cancer Institutes SEER training modules [internet]. 2018 [cited 2018 May 1]. Available from: https://training.seer.cancer.gov/melanoma/anatomy/layers.html

9. US FDA. EMLA® CREAM (lidocaine 2.5% and prilocaine 2.5%).

10. Tadicherla S, Berman B. Percutaneous dermal drug delivery for local pain control. Ther Clin Risk Manag 2006; 2(1):99–113. 11. Numit Product Information. June 2016.

11. Numit Product Information.